By E.L. Cooper, A. Beschin, M. Bilej (editors)
This quantity first provides facts for the earthworm's immune method; the consequences strongly recommend that yes molecules of the earthworm's immune process will be exploited as common antibiotics - therefore the biomedical functions. Earthworms have a powerful immune method on account that melanoma can't be brought on in them, nor does it appear to happen in usual populations. Cytoxicity of melanoma cells has been tested in terms of earthworm leukocytes dependent upon: constitution; phone differentiation antigens; and serve as printed through FACS and mAbs.
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Extra resources for A New Model for Analyzing Antimicrobial Peptides With Biomedical Applications (Nato: Life and Behavioural Sciences, 343)
Cooper / The Earthworm: A New Model 19 first and second days but decreased and normalized by day 17. Because fibrinolytic activities increased, these results suggest that earthworm powder represents a possible oral thrombolytic agent. This earthworm enzyme may be applicable for treating patients with thalassemia. As an attempt to discover possible therapeutic effects previously ascribed to historically recorded traditions, the groups of Mihara et al. and Nakajima et al. [65-68] have obtained strong fibrinolytic enzymes in saline extracts of the earthworm, Lumbricus rubellus.
M. Bilej et al, Phagocytosis of synthetic particles in earthworms: absence of oxidative burst and possible role of lyric enzymes, Folia Biol. 36 (1991) 227-231. M. , Phagocytosis of synthetic particles in earthworms: effect of antigenic stimulation and opsonization, Folia Biol. 36 (1991) 273-280. V. Vetvicka et al. „ Immunology of Annelids, CRC Press Boca Raton Florida (1994) pp. 300. L. Cooper, Transplantation immunity in annelids. I. Rejection of xenografts exchanged between Lumbricus terrestris and Eisenia foetida.
57 (1991) 177-183.  Ph. , Protein analysis of earthworm coelomic fluid. II. Isolation and biochemical characterization of the Eisenia fetida andrei factor (EFAF), Comp. Biochem. Physiol. 69 (1981) 829-836.  A. , Purification, characterization and activities of two hemolytic and antibacterial proteins from coelomic fluid of the annelid Eisenia fetida andrei, Biochim. Biophys. Acta 1337 (1997)123-132. L. Cooper, Phylogeny of cytotoxicity. Endeavor 4 (1981) 160-165. L. Cooper, Comparative immunology: the value of annelids In V.