Download Abl Family Kinases in Development and Disease (Molecular by Anthony Koleske PDF

By Anthony Koleske

Abl relatives Kinases in improvement and disorder presents an summary of the services of Abl kinfolk kinases in improvement and sickness. This new name discusses the biochemical, genetic, and mobilephone organic information that elucidate the mobile roles for those kinases in those approaches.

Show description

Read or Download Abl Family Kinases in Development and Disease (Molecular Biology Intelligence Unit) PDF

Best physiology books

Marks' Basic Medical Biochemistry

This best-selling source makes use of a finished but useful procedure that scholars comprehend. The authors current evidence and pathways to stress how the underlying biochemistry is said to the body's total physiological capabilities. exact case stories convey scholars the connection among biochemistry and scientific difficulties.

Physical Activity and Health Guidelines: Recommendations for Various Ages, Fitness Levels, and Conditions from 57 Authoritative Sources

Sifting during the quite a few instructions on actual task and well-being released by means of executive businesses, expert organisations, and institutions could be a daunting job. details exists in all kinds of codecs and locations—including executive files, press releases, and net sites—so easily discovering these guidance will be a tribulation.

Zinc Signals in Cellular Functions and Disorders

This booklet describes the the most important function of "zinc indications" in organic techniques on a molecular and physiological foundation, discussing destiny instructions and questions underlying this distinct phenomenon. to complete this, a gaggle of globally leaders within the box, who've made remarkable contributions, evaluate zinc signs from a certified point of view.

D-Amino Acids: Physiology, Metabolism, and Application

This ebook provides a accomplished review of the jobs of ᴅ-amino acids and most recent examine findings, to bare their interesting elements and to facilitate greater knowing in their very important roles in body structure and illnesses. It additionally offers worthwhile tricks for the improvement of substances and sensible meals.

Extra info for Abl Family Kinases in Development and Disease (Molecular Biology Intelligence Unit)

Sample text

Adv Cancer Res 2002; 85:51-100. 47. T r u o n g T , Sun G, Doorly M et al. M o d u l a t i o n of D N A damage-induced apoptosis by cell a d h e s i o n is i n d e p e n d e n t l y mediated by p 5 3 and c-Abl. Proc N a t l Acad Sci U S A 2 0 0 3 ; 100(18):10281-10286. 48. Hernandez SE, Settleman J, Koleske AJ. Adhesion-dependent regulation of p l 9 0 R h o G A P in the developing brain by the Abl-related gene tyrosine kinase. Curr Biol 2004; 14(8):691-696. 49. Woodring PJ, Hunter T, W a n g JY.

2 1 . Wertheim JA, Forsythe K, Druker BJ et al. BCR-ABL-induced adhesion defects are tyrosine kinase-independent. Blood 2002; 99(11):4122-4130. 22. Salgia R, Li JL, Ewaniuk DS et al. BCR/ABL induces multiple abnormalities of cytoskeletal function. J Clin Invest 1997; 100(l):46-57. 23. Hurley RW, McCarthy JB, Verfaillie C M . Direct adhesion to bone marrow stroma via fibronectin receptors inhibits hematopoietic progenitor proliferation. J Clin Invest 1995; 96(1):511-519. 24. Lundell BI, McCarthy JB, Kovach N L et al.

Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69(1): 11-25. 2. Schwartz MA, Schaller MD, Ginsberg MH. Integrins: emerging paradigms of signal transduction. Annu Rev Cell Dev Biol 1995; 11:549-599. 3. Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999; 285(5430):1028-1032. Regulation of Cell Adhesion Responses by Ahl Family Kinases 23 4. Plow E F , H a a s T A , Z h a n g L et al. Ligand b i n d i n g t o i n t e g r i n s . J Biol C h e m 2 0 0 0 ; 275(29):21785-21788.

Download PDF sample

Rated 4.50 of 5 – based on 28 votes